Article
The relationship between alcoholism and DBI gene polymorphism in Japanese--genotyping of the +529A/T in DBI gene polymorphism based on PCR.
Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence - 1 Dec 2007
Waga Chikako, Ikeda Kazutaka, Iwahashi Kazuhiko
Abstract excerpt
As a help of elucidate of the pathogenesis of alcohol dependence, we investigated the relationship between the genetic variants of the diazepam biding inhibitor (DBI) gene polymorphism and alcoholism. We analyzed the DBI genotypes using a polymerase chain reaction with confronting two-pair novel primers (PCR-CTPP) method in 180 healthy controls and 43 alcoholic. There was a significant difference in the +529A/T...
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