Article
Blunted cytopenias and weight loss: new correlates of virologic null response to re-treatment of chronic hepatitis C.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Feb 2008
Lindsay Karen L, Morishima Chihiro, Wright Elizabeth C, Dienstag Jules L, Shiffman Mitchell L, Everson Gregory T, Lok Anna S F, Bonkovsky Herbert L, Lee William M, Morgan Timothy R, Ghany Marc G
Abstract excerpt
BACKGROUND & AIMS: Peginterferon with ribavirin therapy for chronic hepatitis C leads to sustained loss of serum hepatitis C virus (HCV) RNA in half of treated patients. Although viral kinetic profiles in treatment responders shed light on the mechanism of action of interferon and ribavirin, minimal information is available to explain why some patients experience little or no virologic suppression. METHODS: We...
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