Article
Hepatitis delta virus heterogeneity: a study by immunofluorescence.
Journal of hepatology - 1 Jan 1991
Negro F, Pacchioni D, Bussolati G, Bonino F
Abstract excerpt
Hepatitis delta virus (HDV)-RNA shows a microheterogeneity at nucleotide 1015 resulting in the production of two co-terminal forms of the HDV-associated antigen (HDAg), referred to as p24 and p27. In vitro experiments have shown that p24 is localized within the nucleolus, while p27 expression is probably confined to the nucleoplasm. The sequential appearance of these two proteins may play a role in the...
Topics
- Antigens, Viral
- Biopsy
- Fluorescent Antibody Technique
- Genetic Variation
- Hepatitis D
- Hepatitis Delta Virus
- Hepatitis delta Antigens
- Humans
- Immunoglobulin G
- Liver
- RNA, Viral