Article
Lessons from the past: familial aggregation analysis of fatal pandemic influenza (Spanish flu) in Iceland in 1918.
Proceedings of the National Academy of Sciences of the United States of America - 29 Jan 2008
Gottfredsson Magnús, Halldórsson Bjarni V, Jónsson Stefán, Kristjánsson Már, Kristjánsson Kristleifur, Kristinsson Karl G, Löve Arthur, Blöndal Thorsteinn, Viboud Cécile, Thorvaldsson Sverrir, Helgason Agnar, Gulcher Jeffrey R, Stefánsson Kári, Jónsdóttir Ingileif
Abstract excerpt
The pandemic influenza of 1918 (Spanish flu) killed 21-50 million people globally, including in Iceland, where the characteristics and spread of the epidemic were well documented. It has been postulated that genetic host factors may have contributed to this high mortality. We identified 455 individuals who died of the Spanish flu in Iceland during a 6-week period during the winter of 1918, representing >92% of...
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