Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Parental-origin-determination fluorescence in situ hybridization distinguishes homologous human chromosomes on a single-cell level.

International journal of molecular medicine - 1 Feb 2008

Weise A, Gross M, Mrasek K, Mkrtchyan H, Horsthemke B, Jonsrud C, Von Eggeling F, Hinreiner S, Witthuhn V, Claussen U, Liehr T

Abstract excerpt

The differentiation of homologous chromosomes as well as their parental origin can presently be conducted and determined exclusively by molecular genetic methods using microsatellite or SNP analysis. Only in exceptional cases is a distinction on a single-cell level possible, e.g. due to variations within the heterochromatic regions of chromosomes 1, 9, 16 and Y or the p-arms of the acrocentric chromosomes. In the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Chromosomes, Artificial, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human

Share to Clone Cells

Share to CNP gene

Share to In Situ Hybridization, Fluorescence

Share to Microsatellite Repeats

Share to Uniparental Disomy

Source

Identifiers

PMID: 18204785
DOI: 10.3892/ijmm.21.2.189

Genes

CNP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Parental-origin-determination fluorescence in situ hybridization distinguishes homologous human chromosomes on a single-cell level.PMID 18204785Read ↗

Parental origin of deletions and duplications – about the necessity to check for cryptic inversionsSemantic proximity Read ↗

Cytogenetic contribution to uniparental disomy (UPD)Semantic proximity Read ↗

Small supernumerary marker chromosomes (SMCs): genotype-phenotype correlation and classification.Semantic proximity Read ↗

Uniparental disomy is a chromosomic disorder in the first placeSemantic proximity Read ↗

Molecular Cytogenetics in the Era of Chromosomics and Cytogenomic ApproachesSemantic proximity Read ↗

Small supernumerary marker chromosomes 1 with a normal phenotype.Semantic proximity Read ↗

Small supernumerary marker chromosomes--progress towards a genotype-phenotype correlation.Semantic proximity Read ↗

Parental origin of apparently balanced <i>de novo</i> complex chromosomal rearrangements investigated by microdissection, whole genome amplification, and microsatellite‐mediated haplotype analysisSemantic proximity Read ↗

FISH characterization of two supernumerary r(1) associated with distinct clinical phenotypes.Semantic proximity Read ↗

Chromosome abnormalities without phenotypic consequences.Semantic proximity Read ↗

Molecular cytogenetic characterization of eight small supernumerary marker chromosomes originating from chromosomes 2, 4, 8, 18, and 21 in three patients.Semantic proximity Read ↗

Small supernumerary marker chromosomes (sSMC) in humansSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.