Article
Natural genetic variation in lycopene epsilon cyclase tapped for maize biofortification.
Science (New York, N.Y.) - 18 Jan 2008
Harjes Carlos E, Rocheford Torbert R, Bai Ling, Brutnell Thomas P, Kandianis Catherine Bermudez, Sowinski Stephen G, Stapleton Ann E, Vallabhaneni Ratnakar, Williams Mark, Wurtzel Eleanore T, Yan Jianbing, Buckler Edward S
Abstract excerpt
Dietary vitamin A deficiency causes eye disease in 40 million children each year and places 140 to 250 million at risk for health disorders. Many children in sub-Saharan Africa subsist on maize-based diets. Maize displays considerable natural variation for carotenoid composition, including vitamin A precursors alpha-carotene, beta-carotene, and beta-cryptoxanthin. Through association analysis, linkage mapping,...
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