Purification and structural study of two albumin variants in an Irish population.

doi:10.1016/0009-8981(91)90229-6

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Article

Purification and structural study of two albumin variants in an Irish population.

Clinica chimica acta; international journal of clinical chemistry - 31 Dec 1991

Sakamoto Y, Davis E, Madison J, Watkins S, McLaughlin H, Leahy D T, Putnam F W

Abstract excerpt

Two types of variant albumins were detected during routine electrophoresis on cellulose acetate on 34,000 sera from patients in a relatively stable Irish population. The fast type (IRE1) (relative mobility 1.05) had a heterozygote frequency of 1/3,780, and the slow type (IRE2) (relative mobility of 0.94) had a heterozygote frequency of 1/8,500. A method for purification of the two types of variants is described....

Topics

Adult
Aged
Aged, 80 and over
Amino Acid Sequence
Chromatography, High Pressure Liquid
Cyanogen Bromide
Electrophoresis, Cellulose Acetate
Female
Genetic Variation
Humans
Hydrogen-Ion Concentration

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Ireland

Isoelectric Focusing

Male

Middle Aged

Molecular Sequence Data

Peptide Fragments

Serine Endopeptidases

Source

Open in PubMed

Identifiers

PMID: 1819460
DOI: 10.1016/0009-8981(91)90229-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1819460-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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