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Article

Multiple forms of atypical rearrangements generating supernumerary derivative chromosome 15.

BMC genetics - 4 Jan 2008

Wang Nicholas J, Parokonny Alexander S, Thatcher Karen N, Driscoll Jennette, Malone Barbara M, Dorrani Naghmeh, Sigman Marian, LaSalle Janine M, Schanen N Carolyn

Abstract excerpt

BACKGROUND: Maternally-derived duplications that include the imprinted region on the proximal long arm of chromosome 15 underlie a complex neurobehavioral disorder characterized by cognitive impairment, seizures and a substantial risk for autism spectrum disorders1. The duplications most often take the form of a supernumerary pseudodicentric derivative chromosome 15 [der(15)] that has been called inverted...

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Identifiers

PMID: 18177502
DOI: 10.1186/1471-2156-9-2
PMCID: PMC2249594

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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