Article
Differentiation of Clostridium botulinum serotype A strains by multiple-locus variable-number tandem-repeat analysis.
Applied and environmental microbiology - 1 Feb 2008
Macdonald Thomas E, Helma Charles H, Ticknor Lawrence O, Jackson Paul J, Okinaka Richard T, Smith Leonard A, Smith Theresa J, Hill Karen K
Abstract excerpt
Ten variable-number tandem-repeat (VNTR) regions identified within the complete genomic sequence of Clostridium botulinum strain ATCC 3502 were used to characterize 59 C. botulinum strains of the botulism neurotoxin A1 (BoNT/A1) to BoNT/A4 (BoNT/A1-A4) subtypes to determine their ability to discriminate among the serotype A strains. Two strains representing each of the C. botulinum serotypes B to G, including...
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