Backseat drivers take the wheel.

Abstract excerpt

Somatic mutations in human cancers are comprised of those that contribute to the oncogenic phenotype, driver mutations, and those that reflect the general patterns of exposure and disrepair but are otherwise noncontributory, passenger mutations. Distinguishing drivers that can be of low frequency in any given tumor type from often more numerous passengers is a key challenge. In this issue of Cancer Cell, Fröhling...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Alleles
• Share to DNA Mutational Analysis
• Share to fms-Like Tyrosine Kinase 3