Article
Classification of hepatitis B virus genotype B into 2 major types based on characterization of a novel subgenotype in Arctic indigenous populations.
The Journal of infectious diseases - 15 Nov 2007
Sakamoto Tomoyuki, Tanaka Yasuhito, Simonetti Josephine, Osiowy Carla, Borresen Malene L, Koch Anders, Kurbanov Fuat, Sugiyama Masaya, Minuk Gerald Y, McMahon Brian J, Joh Takashi, Mizokami Masashi
Abstract excerpt
Hepatitis B virus genotype B (HBV/B) has been classified into 5 subgenotypes. Except for Bj/B1 in Japan, the subgenotypes (Ba/B2-B5) have undergone recombination with HBV/C in the core promoter/precore/core genomic region. Phylogenetic analyses of complete sequences show that the Arctic strains belong to a novel subgenotype (HBV/B6) without the recombination, analogous to what is seen with Bj/B1. Comparison of 50...
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