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Article

Cushing proximal symphalangism and the NOG and GDF5 genes.

Pediatric radiology - 1 Feb 2008

Plett Sara K, Berdon Walter E, Cowles Robert A, Oklu Rahmi, Campbell John B

Abstract excerpt

Proximal symphalangism (SYM1) is an autosomal-dominant developmental disorder of joint fusion. This disorder is best known from famous historical descriptions of two large kindred: Cushing's description in 1916 of the "straight-fingered" Brown family of Virginia and Drinkwater's description in 1917 of the British Talbot family of noble blood, descended from the English war hero John Talbot, the first Earl of...

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Source

Identifiers

PMID: 17994231
DOI: 10.1007/s00247-007-0675-y

Genes

GDF5
NOG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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