Article
On the excess of mental retardation and/or congenital malformations in apparently balanced reciprocal translocations. A critical review of the Leuven data 1966-1991.
Genetic counseling (Geneva, Switzerland) - 1 Jan 1991
Fryns J P, Kleczkowska A, Kubień E, Van Den Berghe H
Abstract excerpt
In this report we review 286 reciprocal translocations (rcpt) diagnosed in Leuven in the period 1966, mid 1991. They were selected from a total number of 82,000 patients karyotyped for constitutional reasons. Special attention is paid to: (1) the phenotypic effect of de novo reciprocal chromosomal rearrangements and (2) the incidence of mental retardation/congenital malformations (MR/CM) in familial rcpt....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.