Article
The collagens of articular cartilage.
Seminars in arthritis and rheumatism - 1 Dec 1991
Eyre D R
Abstract excerpt
Articular cartilage contains at least five genetically distinct types of collagen. Types II, IX, and XI are cartilage-specific and are cross-linked together in a copolymeric network that forms the extracellular framework of the tissue. Fibrils of type II collagen provide the basic architecture. Type XI, a quantitatively minor fibril-forming collagen, is probably copolymerized with type II collagen in the matrix....
Topics
- Amino Acid Sequence
- Animals
- Biomarkers
- Cartilage, Articular
- Collagen
- Humans
- Joint Diseases
- Matrix Metalloproteinase 3
- Metalloendopeptidases
- Molecular Sequence Data
- Mutation
- Osteoarthritis