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Article

Colocalisation of predicted exonic splicing enhancers in BRCA2 with reported sequence variants.

Breast cancer research and treatment - 1 Jul 2008

Pettigrew Christopher A, Wayte Nicola, Wronski Ania, Lovelock Paul K, Spurdle Amanda B, Brown Melissa A

Abstract excerpt

Disruption of the breast cancer susceptibility gene BRCA2 is associated with increased risk of developing breast and ovarian cancer. Over 1800 sequence changes in BRCA2 have been reported, although for many the pathogenicity is unclear. Classifying these changes remains a challenge, as they may d...

Read the complete abstract on PubMed

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Source

Identifiers

PMID: 17899372
DOI: 10.1007/s10549-007-9714-5

Genes

BRCA2
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17899372-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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