Article
The reproductive phenotype in polycystic ovary syndrome.
Nature clinical practice. Endocrinology & metabolism - 1 Oct 2007
Chang R Jeffrey
Abstract excerpt
The symptoms of women with polycystic ovary syndrome (PCOS) include hirsutism and irregular menstrual bleeding due to ovarian androgen excess and chronic anovulation. Typically, these features emerge late in puberty or shortly thereafter. The proposed mechanism(s) responsible for increased ovarian androgen production include heightened theca cell responsiveness to gonadotropin stimulation, increased pituitary...
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