Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Genetics of Very Early Onset Alzheimer Disease

1 Sept 2007

Abstract excerpt

OBJECTIVE: This study was undertaken to clarify the genetics of very early onset Alzheimer disease (VEOAD), defined as AD beginning before age 35. BACKGROUND: Early onset AD (EOAD) is defined by onset of symptoms before age 65, and affected individuals may harbor a mutation in presenilin 1 (PSEN1), presenilin 2 (PSEN2), or amyloid precursor protein. VEOAD is exceedingly rare, and PSEN1 mutations have been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Amyotrophic Lateral Sclerosis Research
Share to Dementia and Cognitive Impairment Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17846513
DOI: 10.1097/wnn.0b013e318145a8c8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Genetics of Very Early Onset Alzheimer DiseasePMID 17846513Read ↗

Molecular diagnosis of autosomal dominant early onset Alzheimer’s disease: an update: Table 1Semantic proximity Read ↗

Molecular genetics of early-onset Alzheimer's disease revisited.Semantic proximity Read ↗

Novel presenilin 1 mutation (S170F) causing Alzheimer disease with Lewy bodies in the third decade of life.Semantic proximity Read ↗

Early-onset familial Alzheimer's disease (EOFAD).Semantic proximity Read ↗

Clinical genetics of Alzheimer's disease.Semantic proximity Read ↗

Genetics of Early-Onset Alzheimer DementiaSemantic proximity Read ↗

Genetics of dementia: update and guidelines for the clinician.Semantic proximity Read ↗

APP, PSEN1, and PSEN2 mutations in early-onset Alzheimer disease: A genetic screening study of familial and sporadic cases.Semantic proximity Read ↗

Early onset familial Alzheimer Disease with spastic paraparesis, dysarthria, and seizures and N135S mutation in PSEN1.Semantic proximity Read ↗

The genetics of Alzheimer disease.Semantic proximity Read ↗

Causative Mutations and Genetic Risk Factors in Sporadic Early Onset Alzheimer’s Disease Before 51 YearsSemantic proximity Read ↗

Identification of PSEN1 mutations p.M233L and p.R352C in Han Chinese families with early-onset familial Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.