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Article

Functional redundancy of extracellular matrix protein 1 in epidermal differentiation.

The British journal of dermatology - 1 Oct 2007

Sercu S, Poumay Y, Herphelin F, Liekens J, Beek L, Zwijsen A, Wessagowit V, Huylebroeck D, McGrath J A, Merregaert J

Abstract excerpt

BACKGROUND: Extracellular matrix protein 1 (ECM1) is a secreted protein expressed in skin. Its dermatological relevance has been highlighted by the discovery of loss-of-function mutations in ECM1 in patients with lipoid proteinosis (LiP). OBJECTIVES: To determine the role of ECM1 in epidermal differentiation by examining gene and protein expression of epidermal differentiation markers in individuals with LiP and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17711528
DOI: 10.1111/j.1365-2133.2007.08114.x

Genes

ECM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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