Article
Dystrophin and disease.
Molecular aspects of medicine - 1 Jan 1991
Hoffman E P, Schwartz L
Abstract excerpt
Recent advances concerning the genetic and biochemical basis of Duchenne and Becker muscular dystrophies have resulted in a good understanding of the etiology of these common dystrophies. An important secondary consequence of the genetic and biochemical research has been the generation of gene-based and protein-based diagnostic tools which enable a 'molecular diagnosis' for patients and their families. This...
Topics
- Amino Acid Sequence
- Base Sequence
- Chromosome Deletion
- DNA
- Dystrophin
- Female
- Heterozygote
- Humans
- Male
- Models, Genetic
- Molecular Sequence Data
- Muscular Dystrophies