Article
Etiology of familial aggregation in melanoma and squamous cell carcinoma of the skin.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Aug 2007
Lindström Linda S, Yip Benjamin, Lichtenstein Paul, Pawitan Yudi, Czene Kamila
Abstract excerpt
BACKGROUND: Melanoma and squamous cell carcinoma of the skin (SCC) have been previously shown to coaggregate in families. To shed light on the etiology, we estimated the relative contributions of genetic and environmental factors on the occurrence of each disease, in addition to their influence on coaggregation of the two diseases. Because the malignancies are dependent on UV radiation, we did separate analyses...
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