Article
Prevalence and progression of diabetes in mitochondrial disease.
Diabetologia - 1 Oct 2007
Whittaker R G, Schaefer A M, McFarland R, Taylor R W, Walker M, Turnbull D M
Abstract excerpt
AIMS/HYPOTHESIS: The aims of this study were (1) to determine the prevalence and rate of progression in diabetes secondary to mitochondrial DNA (mtDNA) mutations; and (2) to determine whether percentage heteroplasmy predicts clinical outcome in patients carrying the m.3243A>G mutation. METHODS: We prospectively assessed 242 patients attending a specialist neuromuscular clinic using a validated mitochondrial...
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