Article
Genetic analysis of non-syndromic craniosynostosis.
Orthodontics & craniofacial research - 1 Aug 2007
Boyadjiev S A
Abstract excerpt
Craniosynostosis is a common malformation occurring in 3-5 per 10,000 live births. Most often craniosynostosis occurs as an isolated (i.e. non-syndromic) anomaly. Non-syndromic craniosynostosis (NSC) is a clinically and genetically heterogeneous condition that has the characteristics of a multifactorial trait. It is believed that each sutural synostosis (e.g. sagittal, coronal) represents a different disease....
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