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Article

An Arg545----Cys545 substitution mutation of the von Willebrand factor in type IIB von Willebrand's disease.

European journal of haematology - 1 Nov 1991

Donnér M, Andersson A M, Kristoffersson A C, Nilsson I M, Dahlbäck B, Holmberg L

Abstract excerpt

Type IIB is a special variant of von Willebrand's disease, characterized by an abnormal von Willebrand factor which shows an increased interaction with platelets. This interaction sometimes causes platelet aggregation and thrombocytopenia in vivo. It involves the glycoprotein-Ib (GPIb) receptor on platelets and corresponding GPIb-binding sites in the von Willebrand factor. We here demonstrate a C----T mutation at...

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Identifiers

PMID: 1761120
DOI: 10.1111/j.1600-0609.1991.tb01858.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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An Arg545----Cys545 substitution mutation of the von Willebrand factor in type IIB von Willebrand's disease.PMID 1761120Read ↗

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