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Article

Characterisation of five factor XI mutations.

Thrombosis and haemostasis - 1 Jun 2007

Mitchell Michael J, Dai Letian, Clarke John B, Bolton-Maggs Paula H B, Savidge Geoffrey F, Alhaq Anwar

Abstract excerpt

A large scale factor XI (FXI) mutation screening program identified a number of novel candidate mutations and previously reported mutations and polymorphisms. Five potential missense mutations were selected for further study; these included two novel missense mutations - Met-18Ile (p.Met1Ile) and Met102Thr (p.Met120Thr), two previously reported missense mutations - Tyr133Ser (Tyr151Ser) and Thr575Met (Thr593Met),...

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PMID: 17549289
DOI: 10.1160/th06-12-0704

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