Article
X-ray crystal structures of human immunodeficiency virus type 1 protease mutants complexed with atazanavir.
Journal of virology - 1 Sept 2007
Klei Herbert E, Kish Kevin, Lin Pin-Fang M, Guo Qi, Friborg Jacques, Rose Ronald E, Zhang Yaqun, Goldfarb Valentina, Langley David R, Wittekind Michael, Sheriff Steven
Abstract excerpt
Atazanavir, which is marketed as REYATAZ, is the first human immunodeficiency virus type 1 (HIV-1) protease inhibitor approved for once-daily administration. As previously reported, atazanavir offers improved inhibitory profiles against several common variants of HIV-1 protease over those of the...
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