Article
[Hepatitis C virus--structure, replication and therapeutical opportunities and the phenomenon of resistance].
Postepy biochemii - 1 Jan 2006
Kowala-Piaskowska Arleta
Abstract excerpt
Genetic material of HCV consists of single-strained RNA. Generation of HCV mutants insensitive to the immune system activity and resistant to used medications seem to be a consequence of HCV genetic variability, unusual replication potential and selection pressure of the host organism. During only one day 10(12) of viral particles may be formed, many of which contain mutations. Selection pressure put by the...
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