Article
Genetic basis for congenital heart defects: current knowledge: a scientific statement from the American Heart Association Congenital Cardiac Defects Committee, Council on Cardiovascular Disease in the Young: endorsed by the American Academy of Pediatrics.
Circulation - 12 Jun 2007
Pierpont Mary Ella, Basson Craig T, Benson D Woodrow, Gelb Bruce D, Giglia Therese M, Goldmuntz Elizabeth, McGee Glenn, Sable Craig A, Srivastava Deepak, Webb Catherine L
Abstract excerpt
The intent of this review is to provide the clinician with a summary of what is currently known about the contribution of genetics to the origin of congenital heart disease. Techniques are discussed to evaluate children with heart disease for genetic alterations. Many of these techniques are now available on a clinical basis. Information on the genetic and clinical evaluation of children with cardiac disease is...
Topics
- Chromosome Aberrations
- Cytogenetic Analysis
- DNA Mutational Analysis
- Heart Defects, Congenital
- Humans
- Mutation