Article
Congenital glioblastoma: a clinicopathologic and genetic analysis.
Brain pathology (Zurich, Switzerland) - 1 Jul 2007
Brat Daniel J, Shehata Bahig M, Castellano-Sanchez Amilcar A, Hawkins Cynthia, Yost Robert B, Greco Claudia, Mazewski Claire, Janss Anna, Ohgaki Hiroko, Perry Arie
Abstract excerpt
Congenital central nervous system (CNS) tumors are uncommon, accounting for 1% of all childhood brain tumors. They present clinically either at birth or within the first 3 months. Glioblastoma (GBM) only rarely occurs congenitally and has not been fully characterized. We examined clinicopathologic features and genetic alterations of six congenital GBMs. Tumors were seen by neuroimaging as large, complex cerebral...
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