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Article

Correlation between mRNA expression level of the mutant COL4A5 gene and phenotypes of XLAS females.

Experimental biology and medicine (Maywood, N.J.) - 1 May 2007

Wang Yunfeng, Zhang Hongwen, Ding Jie, Wang Fang

Abstract excerpt

Alport syndrome (AS) is a progressive hereditary glomerulonephritis presented with hematuria, progressive renal failure, sensorineural deafness, and ocular lesions. Females with X-linked Alport syndrome (XLAS) have variable phenotypes, from asymptomatic hematuria to renal failure. In order to understand the possible mechanism of different phenotypes in female XLAS, we analyzed mRNA expression level of the mutant...

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PMID: 17463160

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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