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Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable.

Experimental animals - 1 Apr 2007

Hashimoto Haruo, Arai Toshiro, Ohnishi Yasuyuki, Eto Tomoo, Ito Mamoru, Hioki Kyoji, Suzuki Ryo, Yamauchi Toshimasa, Ohsugi Mitsuru, Saito Muneo, Ueyama Yoshito, Tobe Kazuyuki, Kadowaki Takashi, Tamaoki Norikazu, Kosaka Kinori

Abstract excerpt

We studied the impact of "IVF - ET" on the glucose tolerance test (GTT), insulin tolerance test (ITT) and adiponectin to investigate differences in the phenotypes of B6J- Irs2(-/-) mice. The B6J-Irs2(-/-) mice (KO-Nat group) were prepared by natural mating. Other mice were produced by IVF-ET used...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17460360
DOI: 10.1538/expanim.56.149

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17460360-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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