Article
Common FMF alleles may predispose to development of Behcet's disease with increased risk for venous thrombosis.
Scandinavian journal of rheumatology - 1 Jan 2000
Rabinovich E, Shinar Y, Leiba M, Ehrenfeld M, Langevitz P, Livneh A
Abstract excerpt
BACKGROUND: Behcet's disease (BD) is an inflammatory disorder of unknown cause, associated with vasculitis. Arterial or venous thrombosis occurs in about 25% of BD patients. Familial Mediterranean fever (FMF) is another inflammatory disorder, which stems from mutations in the FMF gene (MEFV) and shares a number of features with BD. OBJECTIVE: MEFV analysis in patients with BD suggests that mutated MEFV may act as...
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