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Article

A longitudinal study of personality and major depression in a population-based sample of male twins.

Psychological medicine - 1 Aug 2007

Fanous Ayman H, Neale Michael C, Aggen Steven H, Kendler Kenneth S

Abstract excerpt

BACKGROUND: The relationship between personality and psychiatric illness is complex. It is not clear whether one directly causes the other. METHOD: In a population-based sample of male twins (n=3030), we attempted to predict major depression (MD) from neuroticism (N) and extraversion (E) and vice versa, to evaluate the causal, scar, state, and prodromal hypotheses. In a longitudinal, structural equation twin...

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Identifiers

PMID: 17407614
DOI: 10.1017/S0033291707000244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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