Article
Genetic variation at five trimeric and tetrameric tandem repeat loci in four human population groups.
Genomics - 1 Feb 1992
Edwards A, Hammond H A, Jin L, Caskey C T, Chakraborty R
Abstract excerpt
Trimeric and tetrameric short tandem repeats (STRs) represent a rich source of highly polymorphic markers in the human genome that may be studied with the polymerase chain reaction (PCR). We report the analysis of a multilocus genotype survey of 97-380 chromosomes in U.S. Black, White, Mexican-American, and Asian populations at five STR loci located on chromosomes 1, 4, 11, and X. The heterozygote frequencies of...
Topics
- Alleles
- Base Sequence
- DNA
- Gene Frequency
- Genetic Markers
- Genetic Variation
- Genetics, Population
- Genotype
- Heterozygote
- Humans
- Molecular Sequence Data
- Mutation
