Article
The G23 and G25 genes of temperate mycobacteriophage L1 are essential for the transcription of its late genes.
Journal of biochemistry and molecular biology - 31 Mar 2007
Datta Hirock Jyoti, Mandal Prajna, Bhattacharya Rajat, Das Niranjan, Sau Subrata, Mandal Nitai Chanda
Abstract excerpt
Two lysis-defective but DNA synthesis non-defective temperature-sensitive (ts) mutants of mycobacteriophage L1, L1G23ts23 and L1G25ts889 were found to be defective also in phage-specific RNA synthesis in the late period of their growth at 42 degrees C, each to the extent of 50% of that at 32 degrees C. The double mutant, L1G23ts23G25ts889 showed the ts defect in phage RNA synthesis that was nearly additive of...
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