Article
Comparative genomics and DNA array-based genotyping of pandemic Staphylococcus aureus strains encoding Panton-Valentine leukocidin.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases - 1 Mar 2007
Monecke S, Berger-Bächi B, Coombs G, Holmes A, Kay I, Kearns A, Linde H-J, O'Brien F, Slickers P, Ehricht R
Abstract excerpt
Within the last few years, methicillin-resistant Staphylococcus aureus (MRSA) strains encoding Panton-Valentine leukocidin (PVL) have emerged and spread worldwide. This epidemic can be attributed to a small number of distinct clones. The present study used a novel assay, based on multiplex linear DNA amplification and subsequent microarray hybridisation, to simultaneously detect all relevant exotoxins,...
Topics
- Bacterial Toxins
- Disease Outbreaks
- Exotoxins
- Genomics
- Genotype
- Leukocidins
- Methicillin Resistance
- Nucleic Acid Hybridization
- Oligonucleotide Array Sequence Analysis
- Staphylococcus aureus