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Article

Can botulinum toxin put the restless legs syndrome to rest?

Medical hypotheses - 1 Jan 2007

Lim Erle C H, Seet Raymond C S

Abstract excerpt

The restless legs syndrome (RLS), affecting between 3% and 15% of the population, is characterised by an urge to move the legs during wakefulness, associated with a range of unpleasant sensory symptoms, especially when sitting or lying down at night. The symptoms can even be painful, and lead to sleep disturbances and depression. RLS is treated with dopaminergic agents, anticonvulsants, opioids, clonidine and...

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Identifiers

PMID: 17363179
DOI: 10.1016/j.mehy.2007.01.037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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