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Article

Theileria parva live vaccination: parasite transmission, persistence and heterologous challenge in the field.

Parasitology - 1 Aug 2007

Oura C A L, Bishop R, Asiimwe B B, Spooner P, Lubega G W, Tait A

Abstract excerpt

The 'Muguga cocktail' live vaccine, delivered by an infection and treatment protocol, has been widely deployed in Eastern, Central and Southern Africa to protect cattle against East Coast fever, caused by Theileria parva. The vaccine contains 3 component stocks (Muguga, Serengeti-transformed and Kiambu 5). In a previous study, parasites from vaccinated and unvaccinated animals were genotyped with a panel of...

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PMID: 17352850
DOI: 10.1017/S0031182007002557

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Theileria parva live vaccination: parasite transmission, persistence and heterologous challenge in the field.PMID 17352850Read ↗

The persistence of component Theileria parva stocks in cattle immunized with the 'Muguga cocktail' live vaccine against East Coast fever in Uganda.Semantic proximity Read ↗

Monitoring vaccinated cattle for induction and longevity of persistent tick-transmissible infection: Implications for wider deployment of live vaccination against East Coast fever in Tanzania.Semantic proximity Read ↗

Multilocus genotyping of Theileria parva isolates associated with a live vaccination trial in Kenya provides evidence for transmission of immunizing parasites into local tick and cattle populations.Semantic proximity Read ↗

Live immunisation against Theileria parva: containing or spreading the disease?Semantic proximity Read ↗

Limited genetic and antigenic diversity within parasite isolates used in a live vaccine against Theileria parva.Semantic proximity Read ↗

Molecular and immunological characterisation of Theileria parva stocks which are components of the ‘Muguga cocktail’ used for vaccination against East Coast fever in cattleSemantic proximity Read ↗

The persistence of Theileria parva infection in cattle immunized using two stocks which differ in their ability to induce a carrier state: analysis using a novel blood spot PCR assaySemantic proximity Read ↗

The genomes of three stocks comprising the most widely utilized live sporozoite Theileria parva vaccine exhibit very different degrees and patterns of sequence divergence.Semantic proximity Read ↗

A review of recent research on Theileria parva: Implications for the infection and treatment vaccination method for control of East Coast fever.Semantic proximity Read ↗

Molecular characterization of live Theileria parva sporozoite vaccine stabilates reveals extensive genotypic diversity.Semantic proximity Read ↗

Molecular epidemiology of <i>Theileria parva</i> in Eastern Democratic Republic of Congo: Implications to the introduction of the Muguga Cocktail vaccine for East Coast FeverSemantic proximity Read ↗

Molecular characterization and population genetics of Theileria parva in Burundi's unvaccinated cattle: Towards the introduction of East Coast fever vaccine.Semantic proximity Read ↗

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