Article
Tissue culture-induced locus-specific alteration in DNA methylation and its correlation with genetic variation in Codonopsis lanceolata Benth. et Hook. f.
Plant cell reports - 1 Aug 2007
Guo W L, Wu R, Zhang Y F, Liu X M, Wang H Y, Gong L, Zhang Z H, Liu Bao
Abstract excerpt
We have reported recently that tissue culture induced a high level of genetic variation at the primary nucleotide sequence in regenerants of medicinal plant Codonopsis lanceolata. It is not known, however, whether epigenetic variation in the form of alteration in DNA methylation also occurred in these plants. Here, we investigated possible alterations in level and pattern of cytosine methylation at the CCGG sites...
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