Article
Genotyping and drug resistance profile of Candida spp. in recurrent and one-off vaginitis, and high association of non-albicans species with non-pregnant status.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2007
Chong Pei Pei, Abdul Hadi Siti Rohani, Lee Yee Lean, Phan Chin Lee, Tan Boon Chong, Ng Kee Peng, Seow Heng Fong
Abstract excerpt
Recurrent vulvovaginal candidiasis affects women worldwide and the resistance to azole drugs may be an important factor. The extent of strain-to-strain variation within a species and its relationship to the ability of the organism to colonize the vulvovaginal mucosa is not well established. The aims of this study were to compare: (i) the genotypes of Candida strains in sequential infections in patients with...
Topics
- Antifungal Agents
- Candida
- Candidiasis, Vulvovaginal
- DNA, Fungal
- Drug Resistance, Fungal
- Female
- Genotype
- Humans
- Phylogeny
- Pregnancy
- Random Amplified Polymorphic DNA Technique
- Recurrence