Article
Human immunodeficiency virus-1 subtypes and antiretroviral drug resistance profiles among drug-naïve Brazilian blood donors.
Transfusion - 1 Jan 2007
Sá-Ferreira José Antonio, Brindeiro Patrícia Alvarez, Chequer-Fernandez Saada, Tanuri Amilcar, Morgado Mariza Gonçalves
Abstract excerpt
BACKGROUND: Human immunodeficiency virus-1 (HIV-1) genetic variability and its implication on the development of new reagents were investigated by correlating time of infection and resistance to antiretroviral drugs. STUDY DESIGN AND METHODS: Seventy-four plasma samples from Brazilian drug-naïve blood donors were assayed to further develop a panel of biologic reagents to be used in serology and molecular tests....
Topics
- Anti-Retroviral Agents
- Blood Donors
- Brazil
- DNA, Viral
- Drug Resistance, Viral
- HIV-1
- Humans
- Mutation
- Reverse Transcriptase Inhibitors
