Article
A multidrug resistance transporter in Magnaporthe is required for host penetration and for survival during oxidative stress.
The Plant cell - 1 Dec 2006
Sun Chuan Bao, Suresh Angayarkanni, Deng Yi Zhen, Naqvi Naweed I
Abstract excerpt
In prokaryotes and eukaryotes, multidrug resistance (MDR) transporters use energy-dependent efflux action to regulate the intracellular levels of antibiotic or xenobiotic compounds. Using mutational analysis of ABC3, we define an important role for such MDR-based efflux during the host penetration step of Magnaporthe grisea pathogenesis. Mutants lacking ABC3 were completely nonpathogenic but were surprisingly...
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