Article
HLA-G, -E and -F: allelism, function and evolution.
Transplant immunology - 1 Dec 2006
Moscoso J, Serrano-Vela J I, Pacheco R, Arnaiz-Villena A
Abstract excerpt
The major histocompatibility complex class I genes comprise a bunch of classical genes (A, B, C), non-classical genes (E, F and G), pseudogenes and truncated genes. MHC-E, -F and -G are now considered immune "tolerization" molecules, which not only interact with NK cells but with T lymphocyte subsets and other cells and have a role in fetus acceptation. A strong positive directional selection is acting for...
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