Article
Microsatellite null alleles and estimation of population differentiation.
Molecular biology and evolution - 1 Mar 2007
Chapuis Marie-Pierre, Estoup Arnaud
Abstract excerpt
Microsatellite null alleles are commonly encountered in population genetics studies, yet little is known about their impact on the estimation of population differentiation. Computer simulations based on the coalescent were used to investigate the evolutionary dynamics of null alleles, their impact on F(ST) and genetic distances, and the efficiency of estimators of null allele frequency. Further, we explored how...
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