Article
Is autoimmune thyroiditis part of the genetic vulnerability (or an endophenotype) for bipolar disorder?
Biological psychiatry - 15 Jul 2007
Vonk Ronald, van der Schot Astrid C, Kahn René S, Nolen Willem A, Drexhage Hemmo A
Abstract excerpt
BACKGROUND: Both genetic and environmental factors are involved in the etiology of bipolar disorder; however, biological markers for the transmission of the bipolar genotype ("endophenotypes") have not been found. Autoimmune thyroiditis with raised levels of thyroperoxidase antibodies (TPO-Abs) is related to bipolar disorder and may be such an endophenotype. This study was intended to examine whether autoimmune...
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