Article
[Molecular approaches to the Rh blood group system].
Nihon hoigaku zasshi = The Japanese journal of legal medicine - 1 Oct 2006
Kajii Eiji
Abstract excerpt
The Rh system clinically is one of the important blood groups. The major Rh antigens are RhD, RhC/c, and RhE/e, which are carried by two integral membrane polypeptides consisted of 416 amino acids. These polypeptides are encoded by two closely related genes, RHD and RHCE. Both RH genes are composed of ten exons. It is thought that multiple recombinations, nucleotide substitutions, large nucleotide gaps (due to...
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