Article
Synthesis, cytotoxicity and clastogenicity of novel alpha-aminophosphonic acids.
Amino acids - 1 Nov 2007
Naydenova E, Troev K, Topashka-Ancheva M, Hägele G, Ivanov I, Kril A
Abstract excerpt
Alpha-ethyl-N-(phosphonomethyl) glycine is synthesized and characterized by NMR and FAB spectroscopy. The cytotoxicity, clastogenic and antiproliferative effect of 3-ethyl-2-hydroxyl-2-oxo-1,4,2-oxazaphosphorinane, sodium salt of 3-ethyl-2-hydroxyl-2-oxo-1,4,2-oxazaphosphorinane, alpha-ethyl-alpha-N-(hydroxyethylamino) methylphosphonic acid, alpha-ethyl-N-(phosphonomethyl) glycine, alpha-ethyl-N-(phosphonomethyl)...
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