Aldosterone deficiency II (CMO II deficiency) is not the result of a mutation of an MspI restriction site within the CYP11B gene.

doi:10.1007/BF01213103

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Article

Aldosterone deficiency II (CMO II deficiency) is not the result of a mutation of an MspI restriction site within the CYP11B gene.

Human genetics - 1 May 1991

Mayerovà A, Zieger B, Brandis M, von Petrykowski W, Wolff G

Abstract excerpt

We report our investigations of a German family with aldosterone deficiency (CMO II deficiency). Restriction fragment length polymorphism analysis using a P450c11 probe demonstrates that a MspI restriction site mutation within the CYP11B gene cannot be the underlying cause for this defect, as has...

Topics

Adult
Aldosterone
Autoradiography
Blotting, Southern
DNA
Deoxyribonuclease HpaII
Deoxyribonucleases, Type II Site-Specific
Female
Humans
Infant, Newborn
Male
Mutation
Pedigree

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