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Article

Genomic presence of recombinant porcine endogenous retrovirus in transmitting miniature swine

2 Nov 2006

Abstract excerpt

The replication of porcine endogenous retrovirus (PERV) in human cell lines suggests a potential infectious risk in xenotransplantation. PERV isolated from human cells following cocultivation with porcine peripheral blood mononuclear cells is a recombinant of PERV-A and PERV-C. We describe two different recombinant PERV-AC sequences in the cellular DNA of some transmitting miniature swine. This is the first...

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PMID: 17081300
DOI: 10.1186/1743-422x-3-91

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