Article
Characterizing pathogenic processes in Batten disease: use of small eukaryotic model systems.
Biochimica et biophysica acta - 1 Oct 2006
Phillips Seasson N, Muzaffar Neda, Codlin Sandra, Korey Christopher A, Taschner Peter E M, de Voer Gert, Mole Sara E, Pearce David A
Abstract excerpt
The neuronal ceroid lipofuscinoses (NCLs) are neurodegenerative disorders. Nevertheless, small model organisms, including those lacking a nervous system, have proven invaluable in the study of mechanisms that underlie the disease and in studying the functions of the conserved proteins associated...
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