Article
G2019S LRRK2 mutation in familial and sporadic Parkinson's disease in Russia.
Movement disorders : official journal of the Movement Disorder Society - 1 Dec 2006
Pchelina Sofya N, Yakimovskii Andrei F, Ivanova Olga N, Emelianov Anton K, Zakharchuk Andrei H, Schwarzman Alexander L
Abstract excerpt
Among mutations associated with autosomal dominant and sporadic Parkinson's disease (PD) the G2019S substitution in the leucine-rich repeat kinase 2 (LRRK2) gene is the most frequently identified. To estimate its frequency in Russia, we analyzed 208 patients with PD from the Northwestern region o...
Topics
- Adult
- Aged
- Aged, 80 and over
- DNA Mutational Analysis
- Family Health
- Female
- Glycine
- Humans
- Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
- Male
- Middle Aged
- Mutation
- Parkinson Disease
- Protein Serine-Threonine Kinases
- Russia
- Serine